Pyspread is a cross-platform Python spreadsheet application. It is based on and written in the programming language Python.

Instead of spreadsheet formulas, Python expressions are entered into the spreadsheet cells. Each expression returns a Python object that can be accessed from other cells. These objects can represent anything including lists or matrices.

In pyspread, cells expect Python expressions and return Python objects. Therefore, complex data types such as lists, trees or matrices can be handled within a single cell. Macros can be used for functions that are too complex for a single expression.